UC San Diego professor of biology Justin Meyer, who specializes in infectious disease research presents his course The Evolution of Infectious Diseases with special attention to the SARS-CoV-2 virus, the COVID-19 disease and its pandemic spread throughout the world. In this lecture - an overview of the emergence, life-cycle, and evolution of HIV. Series: "The Evolution of Infectious Diseases with Justin Meyer" [Health and Medicine] [Science] [Show ID: 35833]

AIDS/HIV: Past, Present, and Future (Video)

The Evolution of Infectious Diseases with Justin Meyer: Lecture 17 - HIV Evolution

The Last Gift study aims to understand where and how HIV hides in the human body when a person with HIV is taking HIV medications. The Last Gift study tackles these aims by studying people with HIV who are terminally ill from a disease other than HIV, like cancer, ALS, or heart disease. The study follows these volunteers with regular blood draws before the person dies and then examines multiple tissues throughout their bodies after death. From these samples, investigators hope to understand how HIV remains hidden from both the person’s immune system and from current HIV therapy. Results from these studies are designed to help develop ways to clear these reservoirs with future therapies. Dr. Davey Smith, Professor of Medicine and Chief of Infectious Diseases and Global Public Health at UCSD discusses the study and its medical and ethical implications. Series: "Exploring Ethics" [Health and Medicine] [Humanities] [Show ID: 32991]

End-of-Life HIV Research - Exploring Ethics

The California HIV/AIDS Research Program (CHRP) is funding the largest demonstration project of its kind in the US, to determine the acceptability, utilization, adherence, and pharmacokinetics of HIV pre-exposure prophylaxis (PrEP) medication among transgender persons to promote their health and protect their lives. As researchers, participants and healthcare providers explain here, the three CHRP-supported studies across the state use different techniques, such as providing PrEP and hormonal therapy together at a single clinic visit, offering in-depth pharmacokinetic analyses on how the two treatments interact, or creating a custom text messaging app to communicate with providers and offer peer support. Information on how to enroll in the University of California-affiliated studies is included. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 33176]

TransPrEP! HIV Prevention for Transgender Persons in California

Dr. Paul Volberding, professor of medicine at UCSF, was perhaps the leading clinician in the United States in the early days of the HIV epidemic. As a young oncologist finishing his training in the early 1980's, Volberding recalls seeing a young gay man with a previously rare tumor: Kaposi's sarcoma. Little did he know that the underlying immunodeficiency that led to KS would come to define his career. Volberding went on to become the founding chief of the AIDS division at San Francisco General Hospital, where he established the first inpatient AIDS wards and outpatient AIDS clinic. In this interview with Dr. Bob Wachter, chair of UCSF's Department of Medicine, Volberding recalls the early days, including the impact of activism and the fear that he and other clinicians would contract the illness. He also discusses the remarkable progress in turning HIV into a manageable chronic disease and the possibility of finding a cure for AIDS.  Series: "A Life in Medicine: People Shaping Healthcare Today" [Health and Medicine] [Business] [Show ID: 32873]

Dr. Paul Volberding - A Life in Medicine: People Shaping Healthcare Today

UCSF Professor Emeritus Dr. Mark Jacobson is interviewed by Dr. Susa Coffey about his novel "Sensing Light." The book focuses on the HIV/AIDS outbreak from the perspective of the medical professionals who found themselves on the front lines trying to treat this horrific new disease. From the first encounter through the decades of hard work that followed, medical science attempted to identify ways to contain and treat the illness. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 32345]

Sensing Light with Dr. Mark Jacobson

Igor Grant, MD, FRCP(C) pursues research that addresses real world behavioral problems. Studying the intersection of drugs of abuse (primarily methamphetamine) and infection, his work sheds light on the basic mechanisms of injury for people with HIV. He examines inflammation in the context of neurological disorders and measures the impact of chronic stress on Alzheimer's disease caregivers. Dr. Grant joins William Mobley, MD, PhD to discuss his life in science and his fascinating work. Series: "Brain Channel" [Health and Medicine] [Show ID: 32221]

The Intersection of Behavior and Mental Health Through the Lens of Inflammation HIV Alzheimer's Disease and More with Igor Grant - On Our Mind

A profile of Diane Havlir, MD and her work in ending the HIV/AIDS epidemic, from co-founding the much admired Getting to Zero consortium in San Francisco to her Sustainable East African Research on Community Health (SEARCH) study in a fishing village in Kenya. Both efforts include the three pillars that are central to stopping the epidemic – preventing HIV infection with PrEP, testing and treating people immediately upon diagnosis of HIV, and retaining people in HIV care. [Public Affairs] [Health and Medicine] [Show ID: 30496]

Diane Havlir: SEARCHing for the End of AIDS

Sir Richard Branson joins UC San Diego’s Steffanie Strathdee, Patricia Gonzalez-Zuniga, MD, and author Jon Cohen for a discussion on the costs of criminalizing drug use on marginalized communities in Tijuana and elsewhere. Series: "HIV/SIDA: The Epidemic in Tijuana" [Public Affairs] [Health and Medicine] [Show ID: 30862]

Drug Decriminalization and Tijuana’s AIDS Epidemic with Sir Richard Branson

Epidemiologist Steffanie Strathdee of UC San Diego shares stories of her global health team’s intervention efforts that have helped curb the spread of HIV and tuberculosis in Tijuana and other poor regions in the world. Series: "HIV/SIDA: The Epidemic in Tijuana" [Public Affairs] [Health and Medicine] [Show ID: 30181]

Postcard From The Trenches: Tijuana’s Hidden Epidemics of HIV and Tuberculosis with Steffanie Strathdee -- Degrees of Health and Well-Being

John Zaia of City of Hope describe his CIRM Disease Team grant to bring a stem cell-based HIV treatment to clinical trials. Series: "California Institute for Regenerative Medicine" [Health and Medicine] [Science] [Show ID: 25754]

Stem Cell Sound Bites: HIV/AIDS

HIV-related stigma and discrimination are alive and well. Despite civil rights laws and protections related to the disclosure of protected health information, people with HIV often worry about their status being disclosed and when that happens, it can cause serious harm. At the same time, exciting work is being done at UC San Diego and elsewhere to integrate HIV surveillance and clinical data to increase engagement in care. Jeffrey Crowley, a Distinguished Scholar and Program Director of the National HIV/AIDS Initiative at Georgetown Law, describes a new way of thinking about the competing impulses to protect privacy while sharing information that could lead to innovations in care. He examines existing privacy protections, explores how testing and counseling methods have shifted and how big data is impacting HIV treatment and prevention. This program is part of the Exploring Ethics series, presented by the Center for Ethics in Science and Technology. Series: "Exploring Ethics" [Health and Medicine] [Science] [Show ID: 29858]

Personalized Medicine Big Data and Innovating to Improve HIV Care with Jeffrey Crowley -- Exploring Ethics

In the first of a four-part series, UC San Diego epidemiologist Steffanie Strathdee and psychologist Tom Patterson start the story of how their research teams have traced the spread of HIV in Tijuana. It opens at a wound clinic in El Bordo, the section of the Tijuana River Canal where migrants and others shoot heroin and, in some cases, share needles. Dr. Patricia Gonzalez-Zuniga offers first aid as she and her staff recruit participants into Strathdee’s Proyecto El Cuete, a study which focuses on HIV prevention for people who inject drugs. Also featured is the inspiring Susi Leal Ricardi, an HIV-positive outreach worker who was once addicted to heroin and had lived in El Bordo. Leal overcame her addiction, has been clean for 14 years, and with the help of antiretroviral drugs, she has fully suppressed her HIV. She is now El Cuete’s “star promotora.” The HIV/SIDA series is based on the book “Tomorrow Is a Long Time.” Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30005]

El Bordo -- HIV/SIDA: The Epidemic in Tijuana - Episode 1

In the second of a four-part series based on “Tomorrow Is a Long Time: Tijuana’s Unchecked HIV/AIDS Epidemic,” Dr. Jose Luis Burgos guides medical students from UC San Diego and Universidad Autónoma de Baja California as they offer free health care at HFiT, the Health Frontiers in Tijuana clinic at Prevencasa. The segment also features an HIV telemedicine project that spares patients a long journey to CAPASITS, the government-run HIV/AIDS clinic across town, and the Tattoo Removal Clinic, a project led by UC San Diego’s Victoria Ojeda that helps people become more presentable to potential employers. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30006]

The Clinics at Prevencasa -- HIV/SIDA: The Epidemic in Tijuana Episode 2

In the third of a four-part series, photographer Malcolm Linton and writer Jon Cohen tell the stories of Victor, Fernanda, Sergio, Susi, Nelly and others living with HIV who are featured in their photo essay book, “Tomorrow Is a Long Time: Tijuana’s Unchecked HIV/AIDS Epidemic.” Linton and Cohen spent two years interviewing and photographing transgender women, people who inject drugs, sex workers and men who have sex with men in Tijuana, documenting what happened to them over time. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30007]

Living with VIH/SIDA: Tijuana Stories -- HIV/SIDA: The Epidemic in Tijuana Episode 3

In the final installment of the series based on “Tomorrow Is a Long Time: Tijuana’s Unchecked HIV/AIDS Epidemic,” writer Jon Cohen explores what it would take to end the AIDS epidemic in Tijuana by 2030, as called for by UNAIDS. Dr. Davey Smith of UC San Diego argues for aggressive, frequent HIV testing in high-risk groups and shows how cutting-edge genetic science can unravel how the virus moves through communities. Cohen explains the benefits of harm reduction strategies, such as providing clean needles and methadone to thwart HIV transmission. And, in an intervention tailored specifically to this epidemic, Steffanie Strathdee and Tom Patterson’s group at UC San Diego has begun training the Tijuana Police about HIV and urging officers to see drug addiction as a sickness, not a crime. Series: "UCTV Prime" [Public Affairs] [Health and Medicine] [Show ID: 30008]

Ending AIDS -- HIV/SIDA: The Epidemic in Tijuana - Episode 4

From the history and spread of HIV/AIDS to the most recent treatments and prevention strategies, the University of California doctors and researchers are accelerating the progress towards prevention and cure.

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AIDS/HIV: Past, Present, and Future (Video)

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