UK & NETHERLANDS—Following the the AJO Podcast interview with Professor Harry de Koning MD PhD, from the Erasmus University in Rotterdam, who discussed his research published in the New England Journal of Medicine that supports the widespread introduction of computed …

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CT Screening Cuts Lung Cancer Deaths 24 Per Cent—Second Study Confirms

Second Study Confirms Lung Cancer CT Screening Cuts Deaths NETHERLANDS—Erasmus University Medical Center, Rotterdam—Research published in the New England Journal of Medicine has confirmed the viability of computed tomographic (CT) screening for detecting cases of lung cancer early in high-risk …Harry J. de Koning MD PhD

Volume CT Lung Cancer Screening Cuts Cancer Deaths 24 Per Cent

  Audio Journal of Oncology   SAN DIEGO—The first-line treatment of choice for older patients with chronic lymphocytic leukemia (CLL) should now be single agent ibrutinib according to conclusions drawn from the Alliance North American Intergroup Study A041202 reported at …Woyach AJO Prouction MASTER

New Front Line Standard for Older Patients with Chronic Lymphocytic Leukemia

Microbiome Diversity Key To Survival After Allogeneic Hematopoietic Cell Transplantation The Audio Journal of Oncology Podcast SAN DIEGO—Overall survival after allogeneic hematopoietic cell transplantation (allo-HCT) was found to be adversely influenced by a lack of diversity in the intestinal microbiota—before, …Jonathan Peled AudioMedica AJO Podcast

Microbiome Diversity Key To Survival After Allogeneic Hematopoietic Cell Transplantation

Audio Journal of Oncology Reporting from 2018 annual meeting of the American Society of Hematology SAN DIEGO—Individualized therapy decisions that are founded on “genomic fingerprint” data can now be made within seven days for most patients with suspected diagnoses of …John C Byrd Sunday ASH AJO WordPress MASTER

Genomic-led AML Clinical Decision Making Within Seven Days

SAN DIEGO—Patients 70 years old and younger with previously untreated chronic lymphocytic leukemia (CLL) lived longer and had progression of their disease delayed when treated with ibrutinib (an irreversible inhibitor of Bruton’s tyrosine kinase [BTK]) combined with the anti-CD 20 …

Ibrutinib: New Frontline Standard for Chronic Lymphocytic Leukemia?

SAN DIEGO—Patients 70 years old and younger with previously untreated chronic lymphocytic leukemia (CLL) lived longer and had progression of their disease delayed when treated with ibrutinib (an irreversible inhibitor of Bruton’s tyrosine kinase [BTK]) combined with the anti-CD 20 …Shanafelt AJO PodcastMASTER

MUNICH—A “salutary lesson” was reported by researchers investigating therapy for oropharyngeal cancer at the 2018 annual congress of the European Society for Medical Oncology (ESMO). It came from results of the De-ESCALaTE HPVstudy that found patients with low-risk head and …Hisham Mehanna discusses head and neck cancer de-escalation

Head and Neck Cancer Therapy De-Escalation: A “Salutary Lesson”

MUNICH—A leading European oncologist acknowledged the impressive life-extending potential of new drug combinations for metastatic renal cell carcinoma discussed at the 2018 annual congress of the European Society for Medical Oncology (ESMO). Progress was reported with purely immunological approaches—using two …John Haanen Audio Journal of Oncology

Which New Combination for Metastatic Renal Cell Cancer?

MUNICH— A doubling of progression free survival (PFS) and objective response rate (ORR) was observed in patients who had their previously untreated advanced renal cell cancer (RCC) treated with a combination of the vascular endothelial growth factor (VEGF) inhibitor axitinib …Robert Motzer ESMO AJO

Two Drug Combination Doubled Kidney Cancer Progression Free Survival

MUNICH— Anaplastic lymphoma kinase (ALK) inhibitors are as effective in “real world” clinical use for treating patients with non-small cell lung cancer (NSCLC) who test positive for ALK gene rearrangements as they are in clinical studies—even though randomized trials “cherry …Mohammad Jahanzeb AJ0

ALK—Targeted Lung Cancer Drugs Benefited Real World Patients 

MUNICH—The role of poly ADP ribose polymerase (PARP) inhibitors for treating newly diagnosed advanced ovarian cancer was under review at the 2018 annual congress of the European Society for Medical Oncology (ESMO) in the light of findings from the SOLO1 …Jonathan Ledermann AJO

First Line PARP Inhibition For Ovarian Cancer Assessed

BRCA1/2 Ovarian Cancer—Three Years Disease Free with First-Line Olaparib MUNICH—An “unprecedented improvement” in progression free survival (PFS) was observed in the randomized controlled double-blind phase three SOLO1 study of women with newly diagnosed ovarian cancer who had BRCA1/2 mutations and …Kathleen Moore OLAPARIB FIRST LINE IN OVAIAN CANCER

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