 Click To Play These are some verbal notes from a recent meeting I attended. There are some pictures, but it's mostly an audio thing. One thing I forgot to note was that in the Mirror Neuron presentation, an experiment was discussed that focused on sarcasm and the ability of an ASD child to "get it". "A balloon, oh great." Said by 2 different people means two entirely different things depending upon the tone. One person is excited about the balloon and the other is expressing disappointment following the balloon having popped. The ASD kid doesn't pick up on the meaning unless s/he's told to pay attention to the tone prior to hearing the phrase. Only then does the ASD kid "get it" and the appropriate spots light up on the MRI.Running time - a 22 minute beast that I failed to get under 10 minutes for youtube consumption. For Quicktime version, click here(pops)It's pretty rough, but Bonferroni and Venn have been taking up much of my non-sleeping time lately. Enjoy.

Bartholomew Cubbins on Autism

The Neurobiology of Autism - conference notes

 Click To Play For quicktime format click hererunning time = 6m 21s

From the IOM: an N of 1; Ep 31

 Watch the video What does trolling achieve? Self-gratification is the only thing I can think of.

BC on Autism Episode 12: Trolling for... why do they troll?

 Watch the video Anger, anger everywhere, and not a drop to drink.

BC on Autism Episode 11: 2 Angry guys

 Click to Play Formats available: Quicktime (.mov), Flash Video (.flv) running time = 7m 11sec or so.Why the blazes would you ever want to put a mole of nucleotides or oligonucleotides into your mouth? Very simple: because you've been told it'll cure autism, that's why. It'll also cure heavy wallet syndrome, and who really wants a big old lump in your back pocket making the derrier look all lopsided and such? Just a quick look at pH and RNase-induced transesterification. Remember, you have a filthy mouth, whether you swear like Cartman or not.For the RNAphiles, I'm not even getting into depurination or anything. Just the basics.

BC on Autism Episode 15: RNA Quackery: Shaken, Not Stirred

 Click to Play I simply had to go to the source of information about RNA drops curing autism and boy, oh boy.  A feller could have an entire blogging career taking these sales pamphlets / presentations / mockery of science apart, piece by piece.btw, I guess last week's injesting/ingesting/in-jesting fun was either too low-brow or too brief. Come on and give me some affirmation love. Maybe more voice-over video fun is the ticket, but it'll have to wait until this RNA drop series is done.running time: ~9m 30secFormats available: Quicktime (.mov)

Ep 16 Part A: Deeper into the RNA Quagmire

 Click To Play Q: Why would anyone want to get the RNA out of yeast so they can ingest it?A: I don't know, but I know it won't cure Autism.Here's how to do it... Running time: ~3 minutesClick here for Quicktime (pops)

BC on Autism 18: Gettin' the RNA Out (of yeast)

 Click To Play This is it, my heart can't take any more of this talk about RNA curing Autism. No amount of ribobabies could get me to do any more. So here's the last bit I have to say about it. If you buy it and drink it, well, it's on you. But please, spare the kids. Other Formats available: Quicktime (.mov)

Advertising Techniques, RNA, and Autism: BC on Autism Ep 19

 Click to Play I get asked all the time about what therapies or interventions I use for our child. Outside of school we simply live life. That's it, but here are some snippets. Run time is 4min 44sec.Formats available: Quicktime (.mov), Flash Video (.flv)

BC on Autism 20: What do I do for therapy?

 Click to Play Two different short bits dealing with RNA and autism.  One funny and tasty, the other dealing with an ill-informed (euphemism) money hound.  In part 2, the individual actually uses the recent awarding of the Nobel Prize for the discovery of RNAi to help drum up some dollars for the Drinkee Drinkee Cure Autism RNA lady.Runtime is 10 minutes. Formats available: Quicktime (.mov)Tags: skeptic, rna, science, autism, salesman

Frosted mini RNA, a cure for Autism: BC on Autism Ep 22

 Click to Play A recent paper caught my eye since it claimed that the use of the chelation agent, DMSA/Succimer, may contribute to cognitive deficits if used in the absence of lead contamination of an animal model.This is a good paper, but I'm just not entirely convinced the the data. Dunno, maybe it's just me. The bottom line is that if one is convinced by their data that succimer treatment can alleviate lead-induced cognitive deficits, then I believe that one has to be convinced by their data that succimer treatment in the absence of lead contamination induces cognitive defects itself - that's a huge and scary statement.Check it out.Formats available: Quicktime (.mov)Tags: dmps, chelation, autism, experiment, science, succimer

Is DMSA/Succimer use in the absence of high lead a dangerous experiment? BC on Autism Ep 23

 Click to Play A quick look at a paper which allows me to launch into my favorite criticisms of microarray data. In short, most people doing Affy arrays don't have any idea what they're doing. Good for Affy. Bad for science. Bad for the public. These guys even try to pull in autism into their analysis. Blech. Running time ~7minFormats available: Quicktime (.mov), Flash Video (.flv)Tags: science, autism, rna, microarray, blood

BC on Autism 24: Microarray, Schmicroarray

 Click To PlayClick here for QuickTime version Wow. Brian Deer really shows us just how much money someone can make in generating panic over nonsense. One guy in particular is reported to have pulled in almost a million US dollars. I'm in the wrong business.

BC on Autism 25: Brian Deer Shines a Light on the Big Money Earners of the MMR Scare

 Click To Play There has been a number of people touting this paper yet only a few have really read it. Here's the paper in pictures. In short, only about half of the real experiment was done. I can't speculate why the authors stopped short, but I can say that their decision renders this paper almost worthless.Running time ~ 10 minClick here to get the QuickTime version

BC on Autism Ep 26: Revisiting Burbacher 2005

 Click To Play David Kirby tries to reduce the impact of the fact that the California autism rates aren't going down in accordance with a severely reduced exposure to Thimerosal by claiming that California is different because California is getting poisoned by mercury from China.What a load.Running time ~ 10 minutes.Click here for the QuickTime version (pops)

BC on Autism 27: California isn't special

As a scientist and a parent of a child on the spectrum, I wear many hats thoughout the day. I believe the pursuit of understanding the roots of autism and other neurological disorders affecting children to be one of the most important things one might do with their professional and free time. Comments and debate are welcome, abuse is not.

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Bartholomew Cubbins on Autism

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