In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the August issue of DTB (https://dtb.bmj.com/content/59/8). The editors talk about the MHRA's decision to reverse the EMA's decision and allow boron-containing chloramphenicol eye drops to be used in children aged below 2 years. They discuss a scheme in England that allows hospital staff to refer patients who would benefit from extra guidance around their medicines regimen for support from a community pharmacy (https://dtb.bmj.com/content/59/8/114). They also highlight the risk from concurrent opioid and benzodiazepine use (https://dtb.bmj.com/content/59/8/116), and talk about home blood pressure monitoring (https://dtb.bmj.com/content/59/8/119). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

DTB podcast

August 2021. Community pharmacy discharge medicines service: a step towards improved patient safety?

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the July issue of DTB. The editors catch up on developments with proposals for all doctors in the UK to provide financial and non-financial declarations of interest. They discuss the problem of boron in chloramphenicol eye drop products and the impact on treating children aged under 2 years (https://dtb.bmj.com/content/59/7/98). The editors also talk about PPIs for persistent throat symptoms (https://dtb.bmj.com/content/59/7/102), the dose of folic acid for use with methotrexate (https://dtb.bmj.com/content/59/7/103) and a case of a patient who developed severe hypophosphataemia with an oral bisphosphonate (https://dtb.bmj.com/content/59/7/107). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

July 2021 - Chloramphenicol eye drops, boron, infants and fertility

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the June issue of DTB. The list of articles mentioned in this podcast: The Editorial “COVID-19 vaccination in pregnancy” - https://dtb.bmj.com/content/59/6/82 DTB select “Stepping down asthma treatment” - https://dtb.bmj.com/content/59/6/85 Review “Prescribing for pregnancy: managing diabetes” - https://dtb.bmj.com/content/59/6/88 Republished case report “Euglycaemic diabetic ketoacidosis in a 43-year-old woman with type 2 diabetes mellitus on SGLT-2 inhibitor (empagliflozin)” - https://dtb.bmj.com/content/59/6/93 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

June 2021 - COVID-19 vaccination in pregnancy

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the May issue of DTB. In light of the "First do no harm" report, the editorial discusses the need for a mandatory register of payments made by pharmaceutical and medical device companies to healthcare professionals, healthcare organisations and patient support organisations (https://dtb.bmj.com/content/59/5/66). The editors talk about the BTS guideline on long-term use of macrolides (https://dtb.bmj.com/content/59/5/67). The main article explores the use of CAR T-cell therapy (https://dtb.bmj.com/content/59/5/73) and the case report is of a patient who developed quinidine hypersensitivity (https://dtb.bmj.com/content/59/5/77). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

May 2021 - Time for transparency

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the April issue of DTB. The editorial discusses variability in the management of people with severe asthma. The editors talk about a summary of an article on changes in prescribing of statins. The main article explores the use of aspirin for pre-eclampsia and the case report is of a patient who developed omeprazole-induced hypomagnesaemia. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

April 2021 - Asthma, a disease of variability

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the March issue of DTB (https://dtb.bmj.com/content/59/3). The editorial discusses a national safety alert that highlighted the risk of dependence associated with prolonged use of opioids for non-cancer pain and a proposal that all opioid medicines in the UK carry the warning "can cause addiction" (https://dtb.bmj.com/content/59/3/34). The editors talk about an article on the rationale and science behind bisphosphonate holidays (https://dtb.bmj.com/content/59/3/35). The main article explores the risk of nitrosamine contamination in medicines (https://dtb.bmj.com/content/59/3/39) and the case report is of a patient who developed an unusually impressive atorvastatin-induced elevation of serum alkaline phosphatase (https://dtb.bmj.com/content/59/3/43). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Also, DTB is running a short survey to find out what people think of our content. Please visit https://dtb.bmj.com to find a link to the survey.

March 2021 - Opioid safety: striking the right balance

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) discuss the February issue of DTB. This includes an editorial that highlights the benefits associated with the human papillomavirus (HPV) and herpes zoster vaccination programmes (https://dtb.bmj.com/content/early/2021/01/11/dtb.2020.000048). The editors talk about a cohort study, which found that many older people who had recently been prescribed a calcium-channel blocker for hypertension were subsequently given a loop diuretic. The main article reviews the use of prescribing safety indicators to improve outcomes for patients and the case report is of a patient who developed immune checkpoint inhibitor-mediated large vessel vasculitis. Read the issue on the DTB website: https://dtb.bmj.com/content/59/2 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

February 2021 - Why vaccines matter

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) discuss the January issue of DTB (https://dtb.bmj.com/content/59/1). This includes an editorial that highlights the urgent need for more information for the public to support the national COVID-19 vaccination programme (https://dtb.bmj.com/content/59/1/2). The editors talk about the importance of knowing how patients use their medicines at home (https://dtb.bmj.com/content/59/1/3)and discuss advice for population vitamin D supplementation in adults in the UK (https://dtb.bmj.com/content/59/1/7). This month's case report involves two patients who developed severe hypothermia, bradycardia and cardiac arrest in association with risperidone (https://dtb.bmj.com/content/59/1/13). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

January 2021 - COVID-19 vaccination: we need more than the ‘mum test’

In this podcast James Cave (Editor in Chief) and David Phizackerley (Deputy Editor) discuss some of the challenges associated with the national COVID-19 vaccination programme. In particular, they highlight the importance of making information on the vaccines’ safety and efficacy available to help people make an informed decision on vaccination. Read the paper: https://dtb.bmj.com/content/early/2020/11/24/dtb.2020.000071 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

COVID-19 vaccines - getting the information right

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) preview the December issue of DTB. This includes an editorial that discusses the results of a study that suggested that people who took antihypertensive medication at bedtime had a lower risk of a cardiovascular event. The editors talk about a threat to the supply of the Priadel brand of lithium carbonate. They also discuss the use of esketamine for treatment-resistant depression. This month's case report involves an unintentional overdose of hyoscine hydrobromide in a young child. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

December 2020 - Hype and hope of bedtime dosing of antihypertensives

In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) preview the November issue of DTB. This includes an editorial that focuses on the National Institute of Health and Care Excellence's draft guideline on the management of chronic pain, and in particular, the approach to treating chronic primary pain (https://dtb.bmj.com/content/58/11/162). The editors talk about a new patient-held steroid emergency card that has been introduced to help healthcare staff identify adult patients with adrenal insufficiency (https://dtb.bmj.com/content/58/11/163). They also discuss the diagnosis and treatment of orthostatic hypotension. This month's case report involves a patient who developed medication-related osteonecrosis (MRONJ) of the mandible and maxilla (https://dtb.bmj.com/content/58/11/172). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

November 2020 - Chronic pain (analgesia armageddon)

A socially distanced podcast with James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) previewing the October issue of DTB. This includes an editorial that discusses the harms caused by medicines and medical devices and highlights concerns over proposals to speed up the UK licensing process for medicines. The editors talk about an article that looks at the influence of pharmaceutical marketing. They also review three new medicines used to prevent migraines. This month's case report involves a patient with rheumatoid arthritis who received latent tuberculosis infection treatment prior to treatment with a biologic agent, and developed shock with resistant hypotension on re-exposure to rifampicin. Read the full issue: https://dtb.bmj.com/content/58/10 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

October 2020 - Making medicines safer?

As we continue with our socially distanced DTB podcasts James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the September issue of DTB. This includes an editorial discussing the challenges facing commissioning organisations when changes to clinical practice or market authorisation have a significant impact on how biological therapies can be used. The editors highlight a study that showed a lack of adherence to guidelines on direct oral anticoagulant dosing in people with atrial fibrillation and renal impairment, and review an article that discusses the risk of seizures with antidepressants. This month's case report involves an Infant with status epilepticus secondary to systemic lidocaine toxicity from topical application. Read the full issue: https://dtb.bmj.com/content/58/9 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

September 2020 - Dilemmas in commissioning biological therapies

Another socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) who provide an overview of the August issue of DTB. This includes an editorial discussing the changes that have taken place in general practices and the new ways of working that have been developed during the coronavirus pandemic (https://dtb.bmj.com/content/58/8/114). The main article reviews the evidence for using vitamin D and calcium in older people who have osteoporosis (https://dtb.bmj.com/content/58/8/122) and the case report highlights the problems faced by a young man who developed a hyperkinetic reaction to dihydrocodeine (https://dtb.bmj.com/content/58/8/126). Read the full issue: https://dtb.bmj.com/content/58/8. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

August 2020 - Virtual revolution

Another socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor), who provide an overview of the July issue of DTB. This includes an editorial that discusses some of the challenges in supplying low-dose aspirin to pregnant women for prevention of pre-eclampsia, a DTB Forum article by Margaret McCartney on some of the challenges to evidence-based medicine during the coronavirus pandemic and a DTB Select update on the safety of ibuprofen in people with COVID-19. The main article discusses managing antiepileptic drugs before and during pregnancy for women with epilepsy, and this month's case report is of amiodarone-induced diffuse alveolar haemorrhage. Read the full issue: https://dtb.bmj.com/content/58/7 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

Low-dose aspirin for prevention of pre-eclampsia: when over the counter just isn’t

For 50 years, Drug and Therapeutics Bulletin (DTB) has provided rigorous and independent evaluations of, and practical advice on, individual treatments and the overall management of disease for doctors, pharmacists and other healthcare professionals. DTB has always been wholly independent of the pharmaceutical industry, Government and regulatory authorities. DTB is also free of advertising and other forms of commercial sponsorship. * The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

hubhopper

DTB podcast

hubhopper