With so much talk about the Gut microbiome and the role of gut bacteria in health and disease; we often forget that there are other organisms living in the gut such as archaea, bacteriophages, helminths, viruses, and fungi.  In today’s episode we welcome on a world expert in the Mycobiome Dr. Mahmoud Ghannoum. We did a great deep dive into the mycobiome, invasive candidiasis, intestinal permeability, biofilm and generally an expansive view of other players in the microbiome! outline of our talk. 00:00  opening 0:42 Show Intro 2:33 Career, overview  7:39 Good Yeast vs. Harmful Yeast 10:35 Candida Pseudoscience 13:08 Fungal Dysbiosis  14:50 Invasive Candidiasis  20:54 Systemic effects of Invasive Candidiasis  22:33 Detecting Symptoms of Dysbiosis  25:04 Risk Factors for Dysbiosis  27:16 The Challenges of Testing and Diagnosis for Yeast concerns  29:28 Metabolomics and yeast markers 33:30 Nutritional approaches to fungal dysbiosis  36:16 Crohn’s Disease -Yeast connection 37:49 Biofilm and Candida 41:26 Closing thoughts  About Dr. Ghannoum:  Dr. Ghannoum has spent his career study the species of fungi that are living within our body and the role they play in health and disease. Dr. Ghannoum is a  tenured Professor and Director of the Center for Medical Mycology at Case Western Reserve University and University Hospitals Medical Center. He is also the co-founder of BIOHM Health, one of the leading consumer microbiome companies in the United States. And he is the author of the book Total Gut Balance which is an outstanding book about the gut mycobiome.   #mycobiome #microbiome #candidiasis #inflammation #chronicillness SHOW LESS --- Send in a voice message: https://anchor.fm/adam-rinde/message

One Thing with Dr. Adam Rinde

The Mycobiome with Dr. Mahmoud Ghannoum

The One Thing Podcast welcomes Type 1 Diabetes specialist Dr. Jody Stanislaw to discuss her holistic approach to helping Type 1 Diabetes with blood sugar management and more.  (Please see Dr. Jody's social links and bio below)  The show outline is as follows:   (0:00) opening (0:42) Show Intro (3:07) Difference between: Type 1 and Type 2 Diabetes (9:13) Beta Cell Reserve (10:12) Pre-screening for Type 1 Diabetes (T1D) (13:01) Environmental Triggers for TID (14:58) The daily life of a Type 1 Diabetic   (17:24) Insulin Injection and Insulin Pumps (17:45) The Basic Factors of Blood Glucose Management (21:52) TID Myths (24:43) Behavioral and Psychological Aspects of T1D (27:39) What's Lacking in conventional T1D care (33:40) The Dawn Phenomenon (42:13) Dr. Jody's Pillars of Health (46:47) Sleep and Blood Sugar (49:27)Hormonal aspects of Blood Sugar (50:16) Innovations in T1D (54:26) Dr. Jody's online programs and consulting practice overview (1:01:06) Closing   About Dr. Stanislaw:   Dr. Jody Stanislaw received her Doctorate in Naturopathic Medicine in 2007, is a Certified Diabetes Care and Education Specialist, and has lived with type 1 diabetes since the age of 7. Her TEDx talk, Sugar is Not a Treat, has over 2 million views.  Her consulting practice is exclusively for people with Type 1 diabetes and is virtual. She has patients in over 10 countries. In addition to teaching patients how to improve their blood sugars, she also supports patients with critical lifestyle areas such as diet, exercise, sleep, and emotional health.  (....Once Covid hit, after being struck by all the fear and negativity that was going around the world, she was moved to make a positive impact in some way. She decided to start doing inspirational Facebook Lives everyday M-F to share optimism and tips for how we with T1D can stay healthy and positive in these challenging times.  She has done over 150 FB lives since March 2020 and is now reaching more T1Ds than ever before. Her videos have thousands of views, and more and more T1Ds are sending her testimonials about how much her content has helped them....)  From her 40+ years of personal plus professional experience with type 1 diabetes, she teaches life-changing information about how to successfully manage this complex condition that standard medical care often leaves out. She has private programs, online courses, and a monthly T1D training program.  For more info, visit:  www.DrJodyND.com   Dr. Jody's Social Links https://www.drjodynd.com  https://www.facebook.com/DrJodyT1D https://www.facebook.com/drjody.stanislaw https://www.youtube.com/user/DrJodyND  https://www.instagram.com/type1.dr.jody.nd/  https://www.linkedin.com/in/dr-jody-stanislaw-108436a  https://twitter.com/DrJodyND --- Send in a voice message: https://anchor.fm/adam-rinde/message

Better Type 1 Diabetes management with Dr. Jody Stanislaw

In this episode we speak to my Colleague Dr. Alena Guggenheim about hypermobility and Ehlers-Danlos Syndromes.  Dr. Alena Guggenheim is an Assistant Professor of Anesthesiology and Perioperative Medicine at Oregon Health and Science University. She is one of the few Naturopathic Physicians in the world that holds such a prestigious position at a major clinical research institution. Dr. Guggenheim specializes in the care of children and adults with chronic pain and connective tissue disorders. She enjoys working with patients with Ehlers-Danlos Syndrome and associated complex syndromes. In this episode we discuss: EDS and its subtypes Non vascular Ehlers Danlos Syndromes Dysautonomia Mast Cell release Genetics related to EDS and more I am sure you will find Dr. Guggenheim as delightful as I did. She is brilliant, informed, intellectually humble, and quite witty.   Please see her course link on Hypermobility and Ehlers Danlos Syndromes https://carlaguggenheim843.lpages.co/hypermobility-syndromes-register/ and also her professional page https://www.ohsu.edu/providers/alena-guggenheim-nd #ehlersdanlosyndrome #hypermobility #eds #connectivetissue --- Send in a voice message: https://anchor.fm/adam-rinde/message Support this podcast: https://anchor.fm/adam-rinde/support

Hypermobility and Ehlers Danlos Syndromes with Dr. Alena Guggenheim

Going beyond diets and calories and calories out. It is about time that we have professionals that are treating Obesity as a medical imbalance rather than a result of a purely behavioral act.  In this episode  I chat with Karli Burridge an internationally recognized expert in obesity medicine. Karli is a physician assistant and Fellow of the Obesity Medicine Association and earned the Certificate of Advanced Education in Obesity Management in 2017. Karli has been working in obesity management, both surgically and non-surgically, since 2012. During this time, she has developed several medical obesity programs in a variety of healthcare settings. She is a co-author of the Obesity Algorithm® and serves on the Board of Trustees for the Illinois Obesity Society. She is also the co-founder and president of PAs in Obesity Medicine. Karli has received multiple awards from the Obesity Medicine Association for her work in expanding the field of obesity medicine and in furthering obesity education for health care providers. Karli is the founder of GainingHealth.com, which she developed to provide resources and support for health care providers who want to incorporate obesity medicine into their medical practice. She has authored a book on developing an obesity medicine program and provides numerous additional tools for obesity program development through her website. Her mission is to increase the availability of science-based, compassionate obesity treatment to all individuals whose health is impacted by obesity. In this episode we speak about: · Karli’s career route to Obesity Medicine, Her mentors, and influential books · The framework of Obesity as a disease · Key hormones of hunger and satiety: leptin , insulin, Glp-1, ghrelin, and more · Insulin resistance as metabolic derangement · Leptin resistance as a metabolic derangement · The causes of Obesity · Diet, weight loss, and weight regain · Medications for weight loss Her program for health care providers at www.gaininghealth.com #obesity #weightloss #fatloss #insulinresitance #leptinresistance --- Send in a voice message: https://anchor.fm/adam-rinde/message Support this podcast: https://anchor.fm/adam-rinde/support

Obesity Medicine 2.0 with Karli Burridge

As you may be aware the focus of brain health has become more important. Not only are we seeing an uptick in disorders such as autism and ADHD; we are also experiencing population that is living longer. Due to the modern medicine,  lifespan is increasing,  however that might be coupled with declining cognitive function and increased brain disease risk. Understanding neuroinflammation, the underpinning of what drives brain disorders is important if we are going to be able to solve brain dysfunctions. In today’s episode I welcome on a legend in in the functional medicine and regenerative medicine space  Jim LaValle R. Ph. CCN. He has a decorated background in natural medicine functional medicine and regenerative medicine. His unique training in the field of pharmacy, botany, nutrition and naturopathy and over 40 years of clinical and teaching experience has led him to have a firm grasp of how to help people deal with chronic inflammatory conditions. I think you’ll quickly notice that he is beyond exceptional at what he does. He is author of over 20 books you can find out more about him on website www.jimlavalle.com. In this episode we dive deeply into the topic of Metflammation; specifically neural inflammation. This is what happens when the brain is upregulated and as they say on fire. This takes place in conditions such as ADHD, Alzheimer’s disease, autism, anxiety, and many other disorders. In this episode we cover: Mentors Books of Influence Neuroinflammation Core Concepts Glial Cell Activation Excitotoxins Metflammation Drivers of Inflammation CIRS: Chronic Inflammatory Response Syndrome Lab testing Synapsin and Other Treatments More about Jim: James B. LaValle, R.Ph., C.C.N. M.T. DHM, DHPh. N.D.(trad) is an internationally recognized clinical pharmacist, author, and board-certified clinical nutritionist, with over 35 years of clinical experience. LaValle is best known for his expertise in performance health and integrative care with personally seeing thousands of clients over the years. He has an extensive background in natural products, lifestyle, drug/nutrient depletion, and uncovering the underlying metabolic issues that keep people from feeling healthy and vital. He has developed programs for several industries including fitness, professional sports teams and health care companies. Most recently Jim was appointed the Clinical Director of the Pro Football Hall of Fame Performance Health Program. --- Send in a voice message: https://anchor.fm/adam-rinde/message Support this podcast: https://anchor.fm/adam-rinde/support

Neuroinflammation with Jim LaValle

A brief update --- Send in a voice message: https://anchor.fm/adam-rinde/message Support this podcast: https://anchor.fm/adam-rinde/support

Session Break

- The 5 big psychiatric epidemics are: Depression, Pain, Anxiety, Addiction, and Post Traumatic Stress Disorder (PTSD). And, depression is the leading cause of disability worldwide. -  Traditional models are Psychotropic medications and/or counseling. While widely successful this model may fail in certain populations.  t Treatment failures might be due to not accessing certain neural networks and possibly psychospiritual levels that might be needed for healing.   Because of this Psychedelic Medicine and Psychedelic-Assisted Psychotherapy has emerged.  This traditional medicine now has the science and trials to help understand how to apply in a clinical setting  In this episode , I am joined by Dr. Erica Zelfand who will guide us through  Psychedelic-assisted psychotherapy.  She is a perfect guide as she is the instructor of the course called The Science of Psychedelics  Dr. Zelfand gives us some information and highlights on  NMDA, Psilocybin, and Ketamine. We learn about which psychedelics impact Brain Derived Neurotrophic Factor, (BDNF), the Default Mode Network (DMN) which involves the medial prefrontal cortex, posterior cingulate cortex/precuneus and angular gyrus. Also those that act on 5HT-2A receptors, and NMDA-receptors.   The effect of these therapies appear to allow the brain to change, access new resources, become more neuroplastic, and gain psycho spiritual insight. Before long psychedelics, will soon be a legalized part of mainstream psychiatry.  About Dr. Zelfand  Erica Zelfand, ND is a licensed family physician specializing in functional medicine and integrative mental health. Blending conventional pharmaceutical medicine with nutrition, herbal medicine, counseling, psycho-spiritual work, and other therapies gleaned from her international travels, Dr. Z’s philosophy of healing aims to nourish the whole person. She is also a medical writer, teacher, psychedelic facilitation instructor, and the mastermind behind The Science of Psychedelics, an online training for healthcare providers and empowered individuals alike. She consults with clients across the globe through her practice, Simba Health.  To learn more, please visit www.drzelfand.com  Her social handles on - Facebook, twitter, Clubhouse, and linkedin handles are all the same: DrZelfand - She has been so kind to offer a 15% coupon on her course The Science of Psychedelics by using the code : onething  at the checkout.  Resources in the episode Books referenced - PIHKAL: A Chemical Love Story by Alexander Shulgin and Ann Shulgin’s (phenethylamines) TIHKAL: The Continuation; A Chemical Love Story by Alexander Shulgin and Ann Shulgin’s (on Tryptamines) -  Works Cited -  Flight Instructions Bill Richards : -  Resources Cited -  Multidisciplinary Association For Psychedelic Studies  -  Dr. Robin Carhart Harris , UK researcher on Psilocybin   --- Support this podcast: https://anchor.fm/adam-rinde/support

The Science of Psychedelic Medicine with Dr. Erica Zelfand

In this episode I welcome on one of my longtime colleagues Jake Felice, ND, LMP. Dr. Felicie is one of the OG’s of medicinal cannabis. In this episode we go into the Endocannabinoid system (ECS), A 600-million-year-old system that is a “harm-reduction” system as Dr. Felice likes to call it in this article https://ndnr.com/pain-medicine/the-endocannabinoid-system-self-regulating-harm-protection/“ As a stress reduction system, the ECS responds positively not only to cannabinoids, but also to diet, lifestyle, and physical medicine interventions .” We also discuss include terpenes and flavonoids, as well as other non-cannabis botanicals that also affect this receptor system. We talk about Cannabidiol (CBD), Tetrahydrocannabinol(THC) and how they act on the ECS for medicinal benefits. Specifically we go into  known safety profile, how to maximize patient tolerability, how to achieve efficacy, cannabis topicals, other delivery modalities, and relative contraindications. In addition, we discuss the “Entourage effect”.  This topic is so much more than you think! About Dr. Felice: Jake F. Felice, ND, LMP is a cannabis author, clinician, educator and consultant whose vision is to advance the science and practical application of cannabis for medical and recreational markets around the world. Dr. Felice provides world class education experiences by speaking authentically about hemp and cannabis.  He consults with healthcare providers and the general public.  His Category 1 CME courses for doctors, nurses and pharmacists has now been translated into four languages.  Dr. Felice is the founder of Cannabis Matrix Consulting, LLC, and he maintains a regular cannabis blog at drjakefelice.com. Socials: Website https://www.drjakefelice.com/ LinkedIn. https://www.linkedin.com/in/drjake/ YouTube. https://www.youtube.com/user/JakeFelice Facebook https://www.facebook.com/drjakefelice/ Twitter https://mobile.twitter.com/home #cbd #ecs  --- Support this podcast: https://anchor.fm/adam-rinde/support

The Endocannabinoid System with Dr. Jake Felice

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating condition with symptoms of persistent fatigue, neuroinflammation,  post-exertional fatigue, joint pain, nerve pain, muscle pain, sensory hypersensitivity, disturbed sleep, headaches, and bowel changes. It often takes years to get a proper diagnosis and most patients are brushed off as having a psychosomatic illness.  ' Thanks to researchers like our guest Dr. Amy Proal; we know so much more ME/CFS. It turns out there chronic viral and other microbe components that drive a significant part of ME/CFS. These pathogens/pathobionts can set up shop and change DNA, mitochondria, and immune function that contributes to the manifestation of ME/CFS. In this episode , Dr. Proal dives into how viruses find tissue to hide out in, disrupt mitochondria, alter the vagus nerve and how this understanding guides us how in treating ME/CFS Dr. Proal shows us that it is not one infectious organism but multiple co-infections overwhelming the immune system pushing into low function.. If we can help the immune system by reducing the overwhelm ; then we can see good progress.   About our guest: Dr. Proal is a microbiologist who studies the molecular mechanisms by which bacterial, fungal and viral pathogens dysregulate human gene expression, immunity and metabolism. Her work further examines how dysbiosis of the human microbiome and/or the human virome can contribute to chronic inflammatory disease processes. As a member of the research team at Autoimmunity Research Foundation, she has authored papers and written book chapters for organizations like the J.Craig Venter Institute and The Autoimmunity Network, and lectured at the NIH and numerous USA/international conferences. Proal graduated from Georgetown University in 2005 with a degree in biology. In 2012, she obtained a PhD in microbiology from Murdoch University in Australia. Her graduate thesis focused on “Autoimmune disease re-examined in light of metagenomic concepts.” Links to her work  Polybio https://polybio.org/team/amy-proal/  Twitter @microbeminded2 #MyalgicEncephalomyelitisChronicFatigueSyndrome #zerozeroscore #chronicfatiguesyndrome #dysautotonmia#CFS#MECFS #naturopathic #chronicinfections #postviral --- Support this podcast: https://anchor.fm/adam-rinde/support

Chronic Infections and Myalgic Encephalitis / Chronic Fatigue Syndrome with Dr. Amy Proal

"Puberty in Reverse" . That's what Dr. Ginger Nash, refers to the menopausal transition leading into the menopausal years. Even as a guy, that statement really drills down what the menopausal stage can be for some. With anxiety, body composition change, irregular menstruation, and sleep disturbances often presenting as some of the early signs of the menopausal transition,   it can be a distressing time for many women. According to Dr. Nash, only about 10% of women will sail into the menopausal years with no symptoms or major physiologic balances. She speaks about the factors that make the menopausal transition particularly rocky and some ways of approaching those years that is quite refreshing and opening.  And she shares that going through menopause can be supported with lower force interventions and does not necessarily need to involve bio-identical hormone replacement. However, that option may be appropriate in certain situations.  This episode is more than speaking about Menopause. It's also a view into the mind and motivation of one of the most skilled and balanced Naturopathic Physicians in our profession. Dr. Nash is one of the few Doctors that I have come across in my career that can pull the best of our medicine from a deep, compassionate, individualized,  and science based perspective. She shines in not just one area but many domains. So it was a pleasure sharing this time with her and getting to learn more about her process. . About Dr. Nash Dr. Nash earned her doctorate in 1998 from The National University of Natural Medicine in Portland, Oregon. She owns and operates a general medical practice in New Haven, CT that specializes in women's health and chronic immune dysregulation. Dr. Nash has also lectured and taught healthcare programs throughout the U.S. and Canada for practitioners of natural medicine for over two decades. She thoroughly enjoys both clinical work and education. Links in the episode: Dr. Nash's practice www.gingernash.com  Feminology www.feminology.org Feminology Facebook Group https://www.facebook.com/groups/168878283890605/ #zerozeroscore #menopause #personalsummer #menopausaltransition #longevity #womenshealth --- Support this podcast: https://anchor.fm/adam-rinde/support

Menopause with Dr. Ginger Nash

In this episode I welcome on Dr. Laura M. Brown, ND , Author of the newly released book Beyond Digestion: How Gut Health connects to Your Mind, Body, and Soul. Dr. Laura M. Brown, is a registered naturopathic doctor with a functional medicine approach. She focuses on stimulating the body’s natural mechanisms to repair damage and rebuild health. She is a HeartMath Certified Practitioner, a level two Certified Gluten Free Practitioner and holds the designation of ADAPT Trained Practitioner from Kresser Institute, the only functional medicine and ancestral health training company. Titled Miss Teen Ontario at age sixteen, Dr. Brown battled many health challenges of her own, ultimately prevailing through naturopathic medicine. Personally, she writes, gardens, hikes, and entertains on 20 beautiful acres in the heart of Ontario, Canada. Learn more about her practice at southendguelph.ca. In this episode we cover:  Dr. Brown's personal philosophy on gut health Comprehensive stool analysis, cyrex array 3, food sensitivity The three subtypes of tissue transglutaminase antibodies and gluten related issues. Food sensitivities Healing foods Heart Rate Variability training and Heart Math and Gut Health and more Enjoy: #guthealth #digestivehelath Links Her website: https://southendguelph.ca/ --- Support this podcast: https://anchor.fm/adam-rinde/support

Beyond Digestion with Dr. Laura M. Brown

We can't say enough good things about Ben.  His success in founding Lake Washington Physical Therapy in the Seattle area is story in its own. In this episode we discuss Ben's expertise. Ben's professional passion is with core stability, biomechanics, and runners. He sees many running enthusiasts that are working towards an easy 5K fun run as well as those that are training for New York or Boston. He has put on several speed and agility camps and participated in the training of college as well as professional runners. Ben speaks routinely at several of the local running stores (Super Jock and Jill and Everyday Athlete) and high school cross country teams. Ben has also authored two books for IAAF and created over 15 lectures that were presented at USATF, IAAF, WADA, and USOC conferences.   In this episode we go into benefits of running, training modalities, kinetic chain issues, how to train, foot wear, and much more!  References from this episode: Lake Washington Physical Therapy Run Cadence #running #physicaltherapy --- Support this podcast: https://anchor.fm/adam-rinde/support

Running with Ben Wobker, PT, Physical Therapist

Polyphenols fall under the category of phytonutrients.  Which are plant nutrients that confer health benefits.  Polyphenols specifically are food for our microbiota and are involved in housecleaning of potential pathogenic pathobionts.  We should really strive for about 1000mg-1500mg of polyphenols in our diet daily as the evidence is stacking up for their  health benefits for colon health, brain health, cardiovascular health, and overall inflammation support.  In this episode of WIALD (what I am learning daily) I go into the best sources and further unpack polyphenol benefits. The WIALD episodes are snack-size podcast recordings that complement the longer episodes that feature guests from various backgrounds. You are invited to come into my personal learning lab on WIALD. For video versions go to the One Thing Podcast with Dr. Adam Rinde over on youtube. #polyphenols #microbiome #guthealth #inflammation --- Support this podcast: https://anchor.fm/adam-rinde/support

WIALD : A focus on Polyphenols

In this episode I welcome Solomon Ezra Berezin, a health coach from Houston , Texas to speak about meditation and its role in performance and health.  More information can be found at www.soundintegrative.com in our blog section. This episode covers: Meditation unpacked, different forms, and benefits. Vipassana meditation Equanimity; what is it and how can be nourished by meditation. Practical ways people can get involved with meditation. About Solomon Ezra Berezin Solomon is a Certified Transformational Nutrition Coach and former college basketball athlete. His focus as a coach is on improving health and/or sports performance with mindset, meditation, nutrition and fitness, designing a future vision, releasing undesired habits, and more. He has been practicing meditation for several years and so far has experienced two meditation retreats that transformed his life, which we’ll talk about today. He can be found at https://www.solomonezra.com/ #meditation #mindfulness #performance --- Support this podcast: https://anchor.fm/adam-rinde/support

Meditation with Solomon Ezra Berezin

In this episode we speak with a repeat guest Dr. Jessica Pizano who a doctor of clinical nutrition and her clinical teammate Sabrina Vaz who is an expert in Pilates.  They are from Mast Cell Advanced Diagnosis and their unique focus on mast cell disorders brings them in close interaction with patients with Ehlers Danlos Syndrome (EDS).    EDS is a connective tissues disorder that involves hypermobility of joints and sometimes hyperelasticity of tissue. Those who are suffering from it deal with a unique type of Chronic Pain that involves joints that are overly mobile. These patients also have issues with mast cell activation.  The integrative approach that Jessica and Sabrina take is shared on this episode . I found it very empowering and useful information for an often-overlooked and under-treated population of #eds patients.  --- Support this podcast: https://anchor.fm/adam-rinde/support

Integrative Approaches to Ehlers Danlos Syndrome With Dr. Jessica Pizano and Sabrina Vaz

The most engaging conversation between health professionals happens in chance meetings in the hallways. During these moments so much is learned .*One Thing* brings together thought leaders in conversation and we share it with health enthusiasts and learners. Our conversations primarily focus on one significant thing in the arenas of gut health, brain health, metabolism, and aging . Support this podcast: https://anchor.fm/adam-rinde/support

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One Thing with Dr. Adam Rinde

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