On this episode of the podcast, I discuss my approach and strategies to handle grapefruit juice interactions. Grapefruit juice causes drug interactions by inhibiting the CYP enzyme system. More specifically, it inhibits CYP3A4 which is responsible for the breakdown of many medications. Quantity is always an important consideration when assessing grapefruit juice interactions. The more that is taken, typically, the more drug concentrations will be affected. It is important to assess the use of grapefruit juice when your patient has a history of cardiovascular disease, cardiac conditions, pain, mental health disease, or gout as some medications used to treat these diseases can interact with grapefruit juice. If you are looking for more content on drug food interactions, be sure to check out my book in the links below.

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Grapefruit Juice Interactions

On this episode, I cover pantoprazole pharmacology, adverse effects, and drug interactions.

Pantoprazole Pharmacology

On this episode, I discuss rosuvastatin pharmacology, adverse effects, drug interactions and pharmacokinetics. Rosuvastatin is a hydrophilic statin which differs from some of the most commonly used statins like simvastatin and atorvastatin. Rosuvastatin is minimally affected by CYP3A4 drug interactions so that is a small potential advantage over simvastatin and atorvastatin. At dosages of 20-40 mg, rosuvastatin is considered a high intensity statin and can bring down LDL by over 50%.

Rosuvastatin Pharmacology

On this episode, I discuss atorvastatin pharmacology, adverse effects, monitoring parameters, and drug interactions.

Atorvastatin Pharmacology

On this episode, I discuss gemfibrozil pharmacology, adverse effects, and important drug interactions.

Gemfibrozil Pharmacology

On this episode I discuss trospium pharmacology, adverse effects, and important drug interactions you should know.

Trospium Pharmacology

On this episode, I discuss propranolol pharmacology, adverse reactions, and important drug interactions you should know.

Propranolol Pharmacology

On this episode, I discuss quetiapine pharmacology, adverse effects, pharmacokinetics, and drug interactions.

Quetiapine Pharmacology

On this episode, I discuss phenazopyridine pharmacology, adverse effects, and potential drug interactions.

Phenazopyridine Pharmacology

On this episode, I discuss fluvoxamine pharmacology, adverse effects, and most importantly, drug interactions.

Fluvoxamine Pharmacology

On this episode, I discuss oxybutynin pharmacology, drug interactions, and adverse effects.

Oxybutynin Pharmacology

On this episode, I will discuss glyburide pharmacology.

Glyburide Pharmacology

On this episode, I discuss the pharmacology of zaleplon including side effects, drug interactions, and important clinical pearls.

Zaleplon Pharmacology

On this episode, I breakdown the pharmacology of hydrochlorothiazide including adverse effects, drug interactions, and other clinical pearls.

Hydrochlorothiazide Pharmacology

On this episode, I discuss torsemide pharmacology, adverse effects, drug interactions and pharmacokinetics.

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Real Life Pharmacology - Pharmacology Education for Health C...

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