Sheila Collins explains that natriuretic peptides protect mice from the metabolic consequences of a high-fat diet by acting on adipose tissue.

Science Signaling Podcast

Science Signaling Podcast for 25 July 2017: Natriuretic peptide signaling in metabolism

Indu Ambudkar explains why radiation therapy for head and neck cancers causes dry mouth.

Science Signaling Podcast for 6 June 2017: Calcium signaling and dry mouth

Nicole De Nisco and Kim Orth explain that the type 3 secretion system 1 of Vibrio parahaemolyticus initially rewires host cell signaling networks to promote cell survival then later kills the host cell.

Science Signaling Podcast for 16 May 2017: Vibrio rewires host cells

Jonathan Jaggar explains how trafficking of regulatory subunits fine-tunes the activity of BK channels in arterial myocytes to limit vasoconstriction.

Science Signaling Podcast for 9 May 2017: Trafficking of BK channel subunits in arterial myocytes

Science Signaling Chief Scientific Editor Michael Yaffe highlights some of the ways that signaling research can contribute to the Cancer Moonshot.

Science Signaling Podcast for 14 March 2017: The Cancer Moonshot

Saumya Das explains how the protein DDiT4L protects the heart from pathological hypertrophy.

Science Signaling Podcast for 28 February 2017: Balancing autophagy in the stressed heart

Antoine Karnoub explains how increased expression of PTX3 promotes the growth of basal-like breast cancer cells.

Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer

Johannes Hell and Manuel Navedo explain that modification of a particular serine residue affects the activity of the L-type calcium channel Cav1.2 in the brain and vasculature, but not in the heart.

Science Signaling Podcast for 24 January 2017: Tissue-specific regulation of L-type calcium channels

Marc Daëron explains how recruitment of the lipid phosphatase SHIP1 enables trans-inhibition by Fc receptors.

Science Signaling Podcast for 20 December 2016: Trans-inhibition by Fc receptors

Bridget Wilson explains that transient homotypic interactions between pre-B cell receptors promotes survival of acute lymphoblastic leukemia cells.

Science Signaling Podcast for 29 November 2016: Pre-B cell receptor signaling in leukemia

Hagit Eldar-Finkelman describes a peptide that inhibits the kinase GSK-3 through an unusual mechanism and improves symptoms in a mouse model of Alzheimer’s disease.

Science Signaling Podcast for 15 November 2016: A new type of kinase inhibitor

Brian Feldman explains how a secreted protease inhibits diet- and glucocorticoid-induced differentiation of adipocytes.

Science Signaling Podcast for 25 October 2016: How glucocorticoids stimulate fat

Eric Haura describes the identification of new targets for treating lung cancers driven by ALK fusion proteins.

Science Signaling Podcast for 18 October 2016: ALK combination therapies for lung cancer

Benjamin Cravatt, John Teijaro, and Megan Blewett describe how the immunosuppressive drug DMF affects proteins in human T cells.

Science Signaling Podcast for 13 September 2016: DMF and the immune system

Michael Nielsen describes the extent and importance of arginine methylation in the human proteome.

Science Signaling Podcast for 30 August 2016: Human arginine methylome

Periodic audiocasts from Science Signaling, the signal transduction knowledge environment.

hubhopper

Science Signaling Podcast

hubhopper