Dr. Eberhard Scheuer is the founder and the President of the Board of Directors at dHealth foundation and has been a pioneer in using blockchain in the healthcare field. Eberhard holds a Ph.D. in psychology and views healthcare always from the patient’s point of view. He has been a researcher, lecturer, therapist, digital health entrepreneur, and networker for two decades. Eberhard is a psychologist by training and was trained as a clinical psychologist, but mainly worked in the research environment studying at UMass Amherst and University of Tübingen. CONNECT WITH EBERHARD LinkedIn: https://www.linkedin.com/in/eberhardscheuer/ Twitter: https://twitter.com/medrepublik Website: https://dhealth.network/ Related episode - https://soundcloud.com/healthunchained/ep-84-nem-development-for-healthcare-gregory-saive-ceo-ubcdigital Show Notes ●Introduction to Eberhard's background ●What is the use case and vision of dHealth Foundation which was previously called the HIT foundation? ●Tokenizing Health data and how patients should ideally be reimbursed for usage of their health data ●Tracing detection system for Covid and other Illnesses and how those use cases are the best for blockchain ●What is Data privacy and how usage of Blockchain transforms the way to store that data off chain and use blockchain for identity management? ●Partnership with Roche on using patients’ data for one of their Hemophilia drug launches and using blockchain for that launch. ●Alpha and beta testing on the dHealth platform ●What is DHP or Digital Health Point tokens and what kind services can be acquired using these tokens? ●Due to the rules and laws of Switzerland, how is operating a Blockchain company there? What are the Pros and Cons? ●European Society of Organ Transplantation (ESOT) exchange and how blockchain can play an important role in the matching process ●What are the financial and technical challenges which are being worked on to be launched in the coming months? ●What influential book can you recommend? “100 years of solitude” by Gabriel Garcia Marquez ”The Ascent of Money” by Nial Furguson ●What are some of the preferred exercises that you like to do to stay active? Running and Sailing. News Corner https://blog.helium.com/more-than-a-data-point-norada-brings-elderly-care-to-the-peoples-network-f75d7e579fed As most of us know, demand for elderly care services continues to climb higher as each new generation lives longer than the previous one. Norada Corporation has teamed up with Helium, also known as the People’s Network, to enhance communications between at-home elderly care managers, seniors, and care givers. Norada solves this challenge by irradicating the need for a smartphone. Instead, as each caregiver completes their service, they tap a button on their ID badge to automatically log location details to the central cloud database using asset tracking technology from Abeeway. To make all of this possible, Norada needed a long-range IoT wireless network, and Helium fit the bill perfectly. As the fastest-growing wireless network, The People’s Network enables cost efficiencies of only $1 per badge per year. Health Unchained Links Website: healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Health Unchained Podcast

Ep. 88: Community-owned Swiss Healthcare Ecosystem - Eberhard Scheuer (President dHealth Network)

Larry Pang is the head of business development and marketing at IoTeX. IoTeX’s mission is to enable a borderless ecosystem where humans and machines can interact with guaranteed trust, free will, and privacy. IoTeX built the first consumer grade indoor security camera that uses blockchain to secure its users data. It’s called Ucam and anyone can buy one from Amazon for about $50. Before IoTeX, Larry worked as a consultant at Oliver Wyman. IoTeX website: https://iotex.io/ Larry's LinkedIn: https://www.linkedin.com/in/larry-pang/ Show Notes •Larry's background and BizDev role at IoTeX •What is the vision for IoTeX and who founded it? •UCam description and functionalities •Which industry verticals are you focusing on? Why? oSecurity, Healthcare, Supply chain •Data Privacy •Smart Homes, medical devices •Computer vision evolution •Autonomous driving • IoTeX technical specifications (architecture) o Blockchain Protocol and network o IoTeX tokenomics o Data storage and Cloud o Intel SGX o Private key generation o Privacy preserving computation capabilities o Any integration with other Home devices like Alexa, Google, etc. ? •Important applications - Healthnet and Health blocks •IoTeX Growth and scale •IoT Competitive landscape - what other companies are working on similar products/services? •Roadmap for 2021 and beyond •Final Takeaways Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 87: Decentralized IoT Everywhere - Larry Pang (IoTeX)

Kordel France is the co-founder and CEO of Seekar Technologies, which is a AI and blockchain startup seeking to advanced computer vision technology for medical imaging, among other use cases. He is a machine learning engineer with experience in computer vision, augmented reality, GPS, autonomous systems, and optics. Published multiple products in automatic target recognition, signal processing, robotics, and medical imaging. Kordel also spent part of his career at Raytheon as an airframe engineer and studied machine learning at MIT and John Hopkins University. Website: https://seekartech.com/healthcare LinkedIn: https://www.linkedin.com/in/kordel-k-f-10349811b/ Show Notes •Introduction to Kordel's background •Experience in machine learning, computer vision, AI •Goal to replicate consciousness through AI •What is your vision for Seekar technologies and why did you start it? •How did you first hear about blockchain technology? •Which industry verticals are you focusing on? Why? oHealthcare, defense, sports, AgTech •Medical Imaging use case and neural networks for edge intelligence •COVID AI app on App Store •Clarity on the AI process, how it thinks •What is SeekarCoin and why do you need it? •Ethics and engineer’s AI bias •Coded Bias (Netflix movie) •Tokenizing equity and community building •What are the biggest challenges you are facing? •Gaining people’s trust in AI •Federated learning and edge ML •General technical specifications (architecture) of network oBlockchain Protocol oData storage and Cloud oInteroperability with existing database systems •What stage of development is your product today? •Roadmap for 2021 and beyond •If it’s not too personal, what would you consider to be your biggest mistake? •What are your thoughts about the singularity that is supposed to happen in 2045? •If you had to have micro chip implanted in your body, where would you want it to be implanted? •Neuro-security •Favorite book that has influenced you - Frankenstein by Mary Shelley News Corner https://www.fiercehealthcare.com/digital-health/ginger-and-headspace-plan-to-merge-to-scale-up-comprehensive-digital-mental-health Two major mental health platforms have agreed to merge their efforts to reach over 100 million consumers. Ginger, a teletherapy startup, and Headspace, a meditation journey app are planning to close the deal in the last quarter of 2021 to create Headspace Health. According the executives, the combined company will have the world’s largest mental health data set, which will be used to provide highly personalized care to individuals.

Ep. 86: Decentralized Computer Vision - Kordel France (CEO Seekar Technologies)

Kordel France is the co-founder and CEO of Seekar Technologies, which is a AI and blockchain startup seeking to advanced computer vision technology for medical imaging, among other use cases. He is a machine learning engineer with experience in computer vision, augmented reality, GPS, autonomous systems, and optics. Published multiple products in automatic target recognition, signal processing, robotics, and medical imaging. Kordel also spent part of his career at Raytheon as an airframe engineer and studied machine learning at MIT and John Hopkins University. Website: https://seekartech.com/healthcare LinkedIn: https://www.linkedin.com/in/kordel-k-f-10349811b/ Show Notes •Introduction to Kordel's background •Experience in machine learning, computer vision, AI •Goal to replicate consciousness through AI •What is your vision for Seekar technologies and why did you start it? •How did you first hear about blockchain technology? •Which industry verticals are you focusing on? Why? oHealthcare, defense, sports, AgTech •Medical Imaging use case and neural networks for edge intelligence •COVID AI app on App Store •Clarity on the AI process, how it thinks •What is SeekarCoin and why do you need it? •Ethics and engineer’s AI bias •Coded Bias (Netflix movie) •Tokenizing equity and community building •What are the biggest challenges you are facing? •Gaining people’s trust in AI •Federated learning and edge ML •General technical specifications (architecture) of network oBlockchain Protocol oData storage and Cloud oInteroperability with existing database systems •What stage of development is your product today? •Roadmap for 2021 and beyond •If it’s not too personal, what would you consider to be your biggest mistake? •What are your thoughts about the singularity that is supposed to happen in 2045? •If you had to have micro chip implanted in your body, where would you want it to be implanted? •Neuro-security •Favorite book that has influenced you - Frankenstein by Mary Shelley News Corner https://www.fiercehealthcare.com/digital-health/ginger-and-headspace-plan-to-merge-to-scale-up-comprehensive-digital-mental-health Two major mental health platforms have agreed to merge their efforts to reach over 100 million consumers. Ginger, a teletherapy startup, and Headspace, a meditation journey app are planning to close the deal in the last quarter of 2021 to create Headspace Health. According the executives, the combined company will have the world’s largest mental health data set, which will be used to provide highly personalized care to individuals. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Jhonatan Bringas Dimitriades, MD is an executive who works with technologists, developers, medical professionals and patients to deliver the right digital and technical solutions to enhance the diagnosis, treatment, recovery and quality of life of patients around the globe. Personal Website: https://jhonatanbringas.com/ Company Website: lapsihealth.com Twitter: https://twitter.com/drjhonatanMD Dr. Bringas has worked in the implementation of medical technologies in some of the top medical centers worldwide, such as the Mayo Clinic, the Cleveland Clinic, the Panama Clinic, the Hong Kong University Hospital, the AMC UMC Amsterdam and many others. His work is related to medical implementation of technologies, digital health, and innovation in the medical devices area. Jhonatan is a certified Occupational Physician, with postgraduate education in Public Health, Business Strategy and Digital Healthcare solutions. Jhonatan holds a Medical Degree, re-certified in 3 continents and has held the positions of Medical Director, Chief Medical Officer and is currently the Chief Communications Officer of Finnish MedTech NUKUTE, a respiratory / sleep medicine wearable company and the Chief Medical Officer of American DTX startup DiaM Life, in the Diabetes Mellitus space. He is co-founder and CEO of Lapsi Health, an early stage startup developing digital therapeutics starting with solutions for chronic asthma pediatric patients. We talked about the evolution of digital therapeutics and wearables from a medical doctor’s perspective. Although this episode is light on blockchain talk, it was a great conversation about the future of digital health and how we can get there. Show topics •Jhonatan's background •Lapsi Health •Wearables •Digital Therapeutics •Clinical Trials •Doctor's perspective News Corner https://consensyshealth.com/news/press-release/consensys-health-to-acquire-fhirblocks-to-enable-patients-to-exercise-fine-grained-control-of-their-confidential-healthcare-information/ On August 10, 2021, ConsenSys Health agreed to acquire FHIRBlocks, an innovative developer of solutions to support self-sovereign patient-directed fine-grained sharing of protected personal health information. The acquisition includes the transfer of FHIRBlocks’ Intellectual Property, as well as key executives and staff, business activities and relationships, to ConsenSys Health. Currently, slow and error-prone manual processes have largely been used to administer patient data consents, but the introduction of digital communications using Fast Healthcare Interoperability Resources (FHIR) for data-interoperability has shown clear benefits and is now mandated by regulations, such as the U.S. 21st Century Cures Act. In addition, patient and consumer privacy regulations, such as HIPAA, GDPR and CCPA are also mandating new processes. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 85: Value of Digital Therapeutics - Jhonatan Dimitriades, MD (CEO Lapsi Health)

Gregory Saive is an experienced software developer from Belgium who uses the NEM blockchain platform to develop various dapps including an online game called PacNem. He spent time as Head Foundation Developer at NEM. Gregory is founder and CEO of UBC.Digital which publishes content for blockchain developers. He's also the blockchain lead at D Health and works on Symbol from NEM. Website: UBC.Digital Book: https://ubc.digital/symbol-from-nem-the-return-of-the-ninjas/ Twitter: https://twitter.com/eVias PacNem website: https://www.pacnem.com/ dHealth website: https://dhealth.network/ Symbol website: https://symbolplatform.com/ --Show Notes-- •Introduction to Gregory's background •Development experience and career •What is the most important thing you are doing in the blockchain space? •Please describe your organization, UBC Digital for developers •eBook – Symbol from NEM the return of the ninjas •What is the primary benefit of using NEM vs another blockchain network for DLT development? •What healthcare organizations are using NEM and what problems are they trying to solve? •How can development be incentivized using blockchain? •What is Dhealth.network? •How did you come up with Pac-Nem? •What are your thoughts on Ethereum and Cardano development? •What is Symbol Platform and how much traction does it have? •General technical specifications (architecture) of network •What are your thoughts about the singularity that is supposed to happen in 2045? •If you had to have micro chip implanted in your body, where would you want it to be implanted? •Favorite book that has influenced you – Clean Code by Robert C. Martin •Final Takeaways --News Corner-- https://qz.com/2036529/more-than-450-airlines-can-now-use-ibms-digital-health-pass/ On July 22, 2021, international airline reservation system, Amadeus, announced adoption of IBM’s digital health passport solution called IBM Digital Health Pass. The health pass uses IBM’s blockchain technology to allow travel security agents to verify a travel’s covid-19 vaccination status without using a simple QR code scan. --Health Unchained Links-- Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 84: NEM Development for Healthcare - Gregory Saive (CEO UBC.Digital)

Ted Tanner Jr., CTO of Watson Health. Ted was previously the CTO of PokitDok (a major healthcare company which leveraged APIs and the DokChain blockchain platform). PokitDok was acquired by Change Healthcare in 2018. Ted is an engineering executive with extensive experience ranging from startups to public corporations. Focused mainly on growth scale computing he has held architect positions at both Apple and Microsoft and has held instrumental roles in several start-ups, including digidesign (IPO and acquired by Avid), Crystal River Engineering (acquired by Creative Labs), and more. He is on the IAB for the University of South Carolina Computer Science Department as well as the Center for Intelligent Systems and Machine Learning at the University of Tennessee. Ted's website: https://www.tedtanner.org/ IBM Watson Health website: https://www.ibm.com/watson-health Twitter: https://twitter.com/tctjr Topics Overview •Introduction of Ted's background •Journey into healthcare and technology •Experience starting PokitDok and selling to Change Healthcare •When did you first learn about blockchain? •How is blockchain adoption and awareness in healthcare developing globally and domestically? •Web3 •Are you concerned about the impact of quantum computing on the world's data security systems, especially blockchains? •Is the future of AI/ML/FL dependent on a secure blockchain network? •What excites you most about IBM Watson Health? •What is LinuxforHealth? Why is it important? •Regulation of technology •Young people and technology addiction •What advice can you share with young technology entrepreneurs who are looking to reshape the healthcare system? •Philosophical/Personal •What do you believe in that most people would disagree with? •(Not to get political) how can technology be used to address drug taboos in our society? •If it’s not too personal, what would you consider to be your biggest mistake? •Favorite book that has influenced you - How to Read a Book by Mortimer J. Adler •What are your thoughts about the singularity that is supposed to happen in 2045? •If you had to have micro chip implanted in your body, where would you want it to be implanted? •Key Takeaways News Corner On May 20, 2021, The Chopra Foundation, a non-profit organization dedicated to improving health and well-being, announced the availability of their new, free, Never Alone mobile application, which offers individuals the ability to connect, 24/7, with curated volunteers, counselors, mental health experts/professional, local organizations, and hospitals based on their location. The app is a collaboration with CG Creative Studios and leverages the Hedera network which is a decentralized ledger technology that uses acyclic graphs to create an asynchronous Byzantine Fault-Tolerant consensus algorithm. The hashgraph technology is currently patented, and the only authorized ledger is Hedera Hashgraph. The native cryptocurrency of the Hedera Hashgraph system is HBAR. The app allows mental health and wellness experts, from medical professionals to meditation experts, to upload content into a service registry, where it is logged on the Hedera Consensus Service and given a digital fingerprint, providing a guarantee of where that content resides and making it completely tamperproof. Users gain easy access by simply logging into the platform to view trustworthy content that they know has not been altered or falsified. The goal of the initiative is to address the roots of human stress and suffering, advance innovation based on scientific research, and democratize access to wellness resources and everyday tools for those in need. https://www.prnewswire.com/news-releases/chopra-foundation-launches-never-alone-app-powered-by-hedera-to-support-mental-and-emotional-well-being-301296334.html Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 83: Data Philosophy and Web3 - Ted Tanner (CTO IBM Watson Health)

Brian Behlendorf is the Executive Director of the Hyperledger project hosted by the Linux Foundation. He’s written and spoken extensively on open-source software development and communities. In 1999, he co-founded the Apache Software foundation, a non-profit that supports several open source project around key internet technologies. Brian has served on the board of the Mozilla foundation since 2003 and was CTO at the World economic forum. Hyperledger was started in 2015 by the Linux Foundation and hosts some of the most popular enterprise-grade distributed ledger platforms like Hyperledger Fabric, Besu, Indy, and Sawtooth. Brian's Twitter: https://twitter.com/brianbehlendorf Brian's Wikipedia page: https://en.wikipedia.org/wiki/Brian_Behlendorf Hyperledger Website: https://www.hyperledger.org/use Show Notes •Brian's background •When did you first learn about blockchain? •How do you compare the current blockchain revolution to the internet revolution of the 90s? •Linux Foundation involvement in healthcare •Launching Hyperledger •What excites you most about the Hyperledger network and its community? •Does the lack of a native cryptocurrency mean there's less incentivize for Hyperledger developers compared to other smart contract DLTs like Ethereum? Or is it a scaling advantage for Hyperledger? •How close are we to a global self-sovereign identity solution? Indy project •Future of identity •Selective disclosure •BBS+ signatures, •Can we expect real privacy and protection from government surveillance in the future? •WHO Vaccine cards historical insight •Public vs. Private DLT - how to choose the right level of openness for business applications? •How important is community and stakeholder governance when developing a DLT solutions? Philosophical/Personal •What do you believe in that most people would disagree with? •(Not to get political) how can technology be used to address drug taboos in our society? •In your view, what would it take for Bitcoin to lose it's #1 place in total network value (in USD)? •Will you be attending Burning Man this year? •Favorite book that has influenced you – The Making of the Atomic Bomb by Richard Rhodes •If you had to have micro chip implanted in your body, where would you want it to be implanted? •DAW (digital audio workstation) of choice – MIXX, OBS, Twitch •Is it fair to have an open network where people can join with equal voting rights without any previous investment or effort into a project? •Key Takeaways News Corner https://www.coindesk.com/microsoft-azure-service-blockchain-close Microsoft has decided to terminate its Azure-based blockchain-as-a-service platform. According to a recent blog post, Microsoft announced, they have been quietly informing customers on the best way to migrate their data to an alternative of their choosing by Sept. 10. Support for new deployments or member creations has also been discontinued. No official reason for their decision has been shared by the company. In late January 2016, Microsoft offered Azure's DevTest Labs so that Blockchain-related services and partners can decouple the Blockchain technology from virtual machines. Microsoft's short-term goal for the Azure BaaS was to make available a certified blockchain marketplace. The recommended migration destination is ConsenSys Quorum Blockchain Service. Users also could opt to self-manage their blockchains using Virtual Machines. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 82: Open-Source Enterprise - Brian Behlendorf (Executive Director of Hyperledger)

Mathieu Galtier, PhD – Neuroscience and computer science (applied mathematics) background. Chief Product Officer of Owkin which was founded in 2016 and has quickly emerged as a leader in bringing AI and ML technologies to the healthcare industry. We’ll be talking about how blockchain technology and federated learning systems are creating amazing new opportunities in medical research and development. LinkedIn https://www.linkedin.com/in/mgaltier/ Guest Twitter: https://twitter.com/m_galtier Research: https://www.researchgate.net/profile/Mathieu-Galtier MELLODDY: https://www.imi.europa.eu/projects-results/project-factsheets/melloddy Owkin • Origins of Owkin and the healthcare interest - life science company - research oriented - really want to cure cancer o Medical data & Clinical predictive models o Connect platform for Federated Learning • Owkin Tech stack overview o Data prep o Infra: Kubernetes o Application layer: Substra (python, Hyperledger fabric) o Algorithms: any python ML frameworks (pytorch, tensorflow etc) • open source foundation to host Substra framework for distributed computation ML for Healthcare • Why is ML relevant for Healthcare? o Precision medicine: customization of treatment to individual patients based on their medical data. o• Clinical Trials Research challenges and opportunities oFederated Learning for Healthcare • What is Federated Learning? o Model training across distributed datasets. Data is never shared. (opposition centralized computation vs traveling models) o Can you describe how federated learning can solve some of our privacy and security concerns with personal data? o HealthChain project o Melloddy project • What is the HealthChain project's main objective? • MELLODDY consortium - Owkin, NVIDIA, and King’s College London - Have you reached your goals? What's new with this collaboration? • Academic collaboration → HealthChain o Industrial coopetition → Melloddy • BLockchain in Federated Learning • Why is a blockchain relevant for Federated Learning? What is in the blockchain? o Trustless permission regime → smart contracts for details governance / data access regimes o Traceability & reproducibility (no 3rd party to trust) → good for certification o Decentralized orchestration → increase security; no shadow computation o Tokenization of data value through contribution score for training models o Private vs public blockchains: we needed a consortium blockchain o How can blockchain-orchestrated federated learning enable a new method of building AI models? o Models have an identity card describing their genealogy. Their performance can be assessed on 3rd party datasets → models are production / certification ready o Models are the most accurate possible. They serve as the basis (for transfer learning) for numerous data modalities: histology, genomics, chemistry... •What do you believe in that most people would disagree with? o There is no free will • Favorite book that has influenced you o Foundation by Isaac Asimov. Psychohistory: 2 scales individual and population. • Keys to ML in Healthcare  Collaboration  Confidentiality  Compliance News Corner https://www.wired.com/story/microsoft-decentralized-id-blockchain/ Occording to sources, Microsoft has been working on a decentralized identity solution since 2017 and has slowly built out the infrastructure over the past few years.. At the recent Ignite conference, Microsoft announced that it will launch a public preview of its “Azure Active Directory verifiable credentials” spring of 2021. In the NHS pilot, for example, health care providers can request access to professional certifications from existing NHS health care workers, who can in turn choose to allow that access, streamlining a process for transferring to another facility that previously required a much more involved back and forth. U Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 81: Federated Learning with DLT - Mathieu Galtier (CPO Owkin)

Disa Lee Choun, head of Global clinical sciences and operations innovation at UCB, a Belgium-based multi-billion dollar pharmaceutical company. Disa is also co-leading the first PHUSE blockchain working group (non-profit) and was named Top 100 tech women, advisor entrepreneur by the Financial times 100 most influential BAME leader. Disa has years of experience working on technology and innovation especially in the pharmaceutical industry. Her passion is working on closing the gap for patients with unmet needs and exploring/implementing the right technologies (Blockchain, IoT, AI/machine learning, robotics, data discovery tools, and others) to accelerate the implementation of End to End patient solution. Prior to joining the pharmaceutical industry, Disa was a co-founder of an IT company. She has an EMBA and B.S. in Pharmaceutical Chemistry. Guest LI: https://www.linkedin.com/in/disa-l-95bb981/ Company website: https://www.ucb.com/ PHUSE website: https://phuse.global/ Show Notes •Introduction to Disa's background •Why did you get into chemistry and pharma? •How does your experience in pharma shape your understanding of clinical research innovation? •Role as Head of Global Clinical Sciences and Operations at UCB •Smart Contracts for clinical trials •Wearables, IOT, and sensors to improve clinical trials •Incentive mechanisms for better clinical trials •How important is community development for the new "blockchain-enabled" business models. •Favorite scientist of all time •Favorite Book – 7 Seven Habits of Highly Efficient People by Stephen Covey and The Tipping Point by Malcolm Gladwell •Final takeaways News Corner https://www.bostonglobe.com/2021/02/19/business/cape-cod-healthcare-receives-bitcoin-donations-totaling-800k/ An anonymous donor donated bitcoin to Cape Cod Healthcare, a hospital system in my state of Massachusetts. On January 28th and on February 19, the donor, (who has previously donated USD to the hospital), sent about $400k in bitcoin to Cape Cod Healthcare. That’s a total of about $800k in bitcoin which the hospital immediately converted to USD. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 80: Clinical Sciences and Operations Innovation - Disa Lee Choun (UCB)

Ain Aaviksoo, MD, MPH, Chief Medical Officer of Estonia-based Guardtime Health which has rolled out a COVID19 vaccine passport technology called VaccineGuard. Ain has worked as Undersecretary for E-services and Innovation for Estonian government overseeing the digital transformation and innovation of health care, labor and social matters. Dr Aaviksoo obtained MD from University of Tartu and MPH from Harvard University. He has earlier work experience as a physician, senior level civil servant, international level consultant on large system transformation and technology adoption in healthcare, health policy researcher, CEO of public policy think-tank Praxis and as a health-tech entrepreneur. Dr Aaviksoo has published over 20 peer-reviewed articles and contributed into several book chapters on health policy and e-health, he is also regularly presenting as invited keynote speaker on digital services and health care innovation at international events. He is lecturing in various universities on innovation and technology in healthcare. Guest info: https://www.linkedin.com/in/ainaaviksoo/ Guardtime Website: https://guardtime.com/ Show notes •Introduction to Ain's background •What drove you to the healthcare industry? •How did you first hear about blockchain technology? •COVID-19 Vaccination rate statistics and updates globally •COVID-19 Vaccine supply chain expectations •What is the vision for Guardtime as a company? •What is the impact of COVID-19 on pharma supply chain and on Guardtime? •Can you briefly describe Guardtime's services/products/platforms and their technology stacks? oMIDA cybersecurity – work with Verizon oZero-Trust system oGuardtime KSI platform oBlockchain Protocols oVaccineGuard What will be the experience for a regular person getting vaccinated? What are your company milestones goals for 2021? •Integration with medical records •Naturally infected/immune people oHSX - Life Sciences oKSI Cash - Central Bank Digital Currency (CBDC) •Experience working with the Estonian government and the WHO •Any feedback from beta-testers of your platform? •What is Guardtime's business model? •Who are your company partners and major investors? •How would you describe the company culture at Guardtime? Are you hiring? •Outlook for 2021 and beyond •Most influential books you've read – The Information: A History, a Theory, a Flood by James Gleick. Team of Teams : New Rules of Engagement for a Complex World by Stanley McChrystal •Final Takeaways News Corner https://www.npr.org/sections/goatsandsoda/2021/02/10/966304438/up-against-mutants-who-says-astrazeneca-vaccine-is-still-a-good-bet. In recent months, there have been more reports of new variants of the coronavirus across different parts of the world. In South Africa, there were plans to distribute millions of AstraZeneca-Oxford covid vaccines (viral vector genetically modified virus type) until some new evidence suggested the vaccine provided “minimal protection” against mild or moderate cases involving the B.1.351 variant also known as 501.V2. The plan would be to still rollout some of the AstraZeneca vaccine but in limited quantities and to monitor recipients closely to see how well it's working. In terms of doses that have so far been purchased, AstraZeneca is currently the world's largest source of COVID vaccines, scheduled to deliver more than 2 billion doses this year. One thing that seems safe to say is getting a vaccine now is better than waiting for a perfect vaccine a year from now. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 79: Smart Vaccination Passports - Ain Aaviksoo, MD, MPH (CMO Guardtime)

Shadrack Kubyane, co-founder of Coronet Blockchain, is a former Deloitte management consultant. He founded the company with his wife, Pretty, to track the supply chain of human hair extensions to salons and individuals in South Africa. Coronet Blockchain leverages IBM Hyperledger technologies to secure the supply chain for human hair extensions. Guest Info Website: https://www.coronetblockchain.com/ LinkedIn: https://www.linkedin.com/in/shadrack-kubyane-04629b12/ Show Notes •Introduction of Shadrack's background and experience •Origins of Coronet Blockchain •Problems that Coronet Blockchain is trying to solve •Hair market in Africa and globally - supply chain •Buyers and sellers of human hair •How can hair extensions improve self-esteem and possibly mental health? •Technology stack •How is the IBM blockchain eco-system? •What kind of data is collected in the Coronet Blockchain marketplace? •Do you need to use blockchain for your marketplace? Why? •What are the main challenges and opportunities that your company faces today? •Company traction •Growth marketing strategies in Africa •Roadmap for 2021 and beyond •If it’s not too personal, what would you consider to be your biggest mistake? •Favorite book that most influenced your universe – Finding a Way to Win: The Principles of Leadership, Teamwork, and Motivation by Bill Parcells •Final takeaways News Corner https://www.mobihealthnews.com/news/emea/astrazeneca-estonia-participate-vaccineguard-pilot In January of 2021, AstraZeneca in Estonia partnered with data security and blockchain firm, Guardtime, to participate in their VaccineGuard pilot. Iceland, Hungary, and Estonia are the first countires to sign up to the new platform supporting the global covid-19 vaccination program. Vaccination passports and the idea of immunity passports are hot topics as people try to get back to normal life. This is just one of many types of digital health technologies being used to facilitate the global rollout of the Covid19 vaccines. While this is a great step forward for the world, there are still many questions about how effective the vaccines are against new coronavirus variants. Tune into Health Unchained episode 79 where we do a deep dive into this pilot project with the Chief medical officer of Guardtime as my guest. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 78: Detecting Counterfeit Hair Extensions in Africa - Shadrack Kubyane (CEO Coronet Blockchain)

Shadrack Kubyane, co-founder of Coronet Blockchain, is a former Deloitte management consultant. He founded the company with his wife, Pretty, to track the supply chain of human hair extensions to salons and individuals in South Africa. Coronet Blockchain leverages IBM Hyperledger technologies to secure the supply chain for human hair extensions. Guest Info Website: https://www.coronetblockchain.com/ LinkedIn: https://www.linkedin.com/in/shadrack-kubyane-04629b12/ Show Notes •Introduction of Shadrack's background and experience •Origins of Coronet Blockchain •Problems that Coronet Blockchain is trying to solve •Hair market in Africa and globally - supply chain •Buyers and sellers of human hair •How can hair extensions improve self-esteem and possibly mental health? •Technology stack •How is the IBM blockchain eco-system? •What kind of data is collected in the Coronet Blockchain marketplace? •Do you need to use blockchain for your marketplace? Why? •What are the main challenges and opportunities that your company faces today? •Company traction •Growth marketing strategies in Africa •Roadmap for 2021 and beyond •If it’s not too personal, what would you consider to be your biggest mistake? •Favorite book that most influenced your universe – Finding a Way to Win by André Olivier •Final takeaways News Corner https://www.mobihealthnews.com/news/emea/astrazeneca-estonia-participate-vaccineguard-pilot In January of 2021, AstraZeneca in Estonia partnered with data security and blockchain firm, Guardtime, to participate in their VaccineGuard pilot. Iceland, Hungary, and Estonia are the first countires to sign up to the new platform supporting the global covid-19 vaccination program. Vaccination passports and the idea of immunity passports are hot topics as people try to get back to normal life. This is just one of many types of digital health technologies being used to facilitate the global rollout of the Covid19 vaccines. While this is a great step forward for the world, there are still many questions about how effective the vaccines are against new coronavirus variants. Tune into Health Unchained episode 79 where we do a deep dive into this pilot project with the Chief medical officer of Guardtime as my guest. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Wendy M. Charles, PhD, CIP, CCRP, CBP is a researcher and regulatory compliance scientist with expertise in managing clinical research operations, quality assurance, and implementation of health information technologies. She has 28 years of research experience; 16 years of management experience with industry-sponsored and federally funded research. Wendy is Chief Scientific Officer at BurstIQ, co-chair of the IEEE Standards Development Working group for blockchain in healthcare and life sciences, and has contributed to numerous other blockchain/healthcare publications. BurstIQ Website: www.burstiq.com Blockchain Compliance by Design: Regulatory Considerations for Blockchain in Clinical Research: https://www.frontiersin.org/articles/10.3389/fbloc.2019.00018/full We talk about how we can start encouraging an ethics by design approach to building software and how dynamic consent management can provide more control over a patient’s own health data. Related episode: https://soundcloud.com/healthunchained/ep-56-securing-health-connections-frank-ricotta-ceo-burstiq IEEE HEALTHCARE VIRTUAL SERIES: BLOCKCHAIN & AI: https://attend.ieee.org/healthcare-blockchain-ai/ Show Notes •Introduction to Wendy's background •What drove you to the healthcare world? •How did you first hear about blockchain technology? •How does your academic research experience influence your perspectives in healthcare infotech industry? •Digital tattoos for temporary health monitoring •Impact of COVID-19 on Clinical research operations •Importance of Ethics by Design •World leadership summit link - https://worldleadersummit.com/topicscategories/blockchain/ •Dynamic Consent management, broad and specific consent •Describe your role as CSO at BurstIQ •What tactics is BurstIQ employing to address data privacy and personal ownership of one's data? •Customers like Intermountain Healthcare saved ~$90M over three years by using BurstIQ: https://www.burstiq.com/burstiq-brings-90-million-case-study-to-blockchain-through-intermountain-healthcare-spin-off-empiric-health/ •What are the biggest barriers to blockchain adoption in healthcare? •Balancing between regulatory compliance and technology innovation •Most influential book you've read – The Patient Will See You Now by Dr. Eric Topol •What are your thoughts about the singularity that is supposed to happen in 2045? •If you had to have micro chip implanted in your body, where would you want it to be implanted? •Thoughts on Neuralink technology •Final Takeaways News Corner https://deepmind.com/blog/article/alphafold-a-solution-to-a-50-year-old-grand-challenge-in-biology Alphabet’s decade old DeepMind artificial intelligence system has essentially solved a 50 year old grand challenge in biology. That problem is known as the protein folding problem. Proteins are the building blocks and operate all our functional biology systems. They are large complex molecules made up of chemical chains and amino acids. This is important because, right now, in order to figure out how a specific protein looks like and how it physically conforms in 3D space, scientists typically use X-Ray crystallography techniques which costs over $100k and takes up to a year to complete. There are currently over 200 million proteins in the main database and only about 170,000 have their 3D structures mapped out, a fraction of the 200M. This research is currently being peer-reviewed for final publication and scientists are absolutely excited about exploring this amazing technology for the advancement of scientific knowledge. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 77: Data Ethics and Compliance - Wendy M. Charles, PhD, CIP, CCRP, CBP

Robert Chu is the Co-founder & CEO of Embleema. He is the former SVP of Global Technology for IQVIA & has created & managed data networks in over 20 countries in the U.S., Asia & Europe. Robert and I talk about the tremendous value of provable, secure real world data that can be directly shared by patients to improve bio-statistical models. We also discuss his recent business partnership with Alira Health and the origins of the HIVE data analytics platform. Embleema Website: https://embleema.com/ Disclaimer: The Health Unchained podcast is for informational and entertainment purposes only and we are not providing any sort of legal, financial, or medical advice. Please do your own research and due diligence before making any important decisions related to these matters. Topics Overview •Introduction to Robert's background •What drove you to the healthcare industry? •Experience at IBM, IMS Health, and IQVIA •How did you first hear about blockchain technology? •What is the vision for Embleema? Why did you start it? •Impact of COVID-19 on on Embleema •Epilepsy Foundation partnership and Epilepsy Digital Engagement Navigator (EDEN) •Long-term studies are difficult to track •Why should people care about real world evidence/data? •Can you describe Embleema's services/products/platforms and their technology stacks? •Hyperledger •HIVE – High Performance Integrated Virtual Environment – data repository and analytics platform built by Dr. Vahan Simonyan who transferred HIVE property to Embleema https://en.wikipedia.org/wiki/High-performance_Integrated_Virtual_Environment •Tracking patient consent •What tactics are you employing to address data privacy and personal ownership of one's data? •Any feedback from beta-testers of your platform? •What are the biggest barriers to blockchain adoption in healthcare? •Synthetic control arms in clinical studies – simulation of placebo group •Embleema's business model? •Company partners and major investors? •Alira Health Partnership goals •How would you describe the company culture at Embleema? •Outlook for 2021 and beyond •Favorite DLT projects doing important work •Most influential book you've read – The Lorax by Dr. Seuss •Thoughts about the singularity that is supposed to happen in 2045 •If you had to have micro chip implanted in your body, where would you want it to be implanted? •Final Takeaways News Corner https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-covid-19-test-self-testing-home On November 17, 2020, the FDA issued an emergency use authorization for the first COVID-19 diagnostic at-home self-test which provides rapid results. The Lucira COVID-19 All-In-One Test Kit is a molecular (real-time loop mediated amplification reaction) single use test that is intended to detect the novel coronavirus SARS-CoV-2 that causes COVID-19. The Lucira COVID-19 All-In-One Test Kit test has been authorized for home use with self-collected nasal swab samples in individuals age 14 and older who are suspected of COVID-19 by their health care provider. Health Unchained Links Website: https://healthunchained.org Telegram: t.me/healthunchained Twitter: twitter.com/Healthunchaind

Ep. 76: Patient-Driven Real World Data - Robert Chu (CEO Embleema)

Health Unchained conducts and facilitates interviews and conversations with healthcare leaders, executives, entrepreneurs, researchers, and medical professionals who are working on interesting and important projects enabled by blockchain technology.

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Health Unchained Podcast

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